Some days ago, this HPE customer advisory caught my attention:
Advisory: (Revision) VMware – HPE ProLiant Gen8 Servers running VMware ESXi 5.5 Patch 10, VMware ESXi 6.0 Patch 4, Or VMware ESXi 6.5 May Experience Purple Screen Of Death (PSOD): LINT1 Motherboard Interrupt
And there is also a corrosponding VMware KB article:
It isn’t clear WHY this setting was changed, but in VMware ESXi 5.5 patch 10, 6.0 patch 4, 6.0 U3 and, 6.5 the Intel IOMMU’s interrupt remapper functionality was disabled. So if you are running these ESXi versions on a HPE ProLiant Gen8, you might want to check if you are affected.